Natural products : drug discovery and therapeutic medicine / edited by Lixin Zhang, Arnold L. Demain.

Includes bibliographical references and index.

Natural products and drug discovery / Arnold L. Demain and Lixin Zhang -- Integrated approaches for discovering novel drugs from microbial natural products / Lixin Zhang -- Automated analyses of HPLC profiles of microbial extracts: a new tool for drug discovery screening / Jose R. Tormo and Juan B. Garcia -- Manipulating microbial metabolites for drug discovery and production / C. Richard Hutchinson -- Improving drug discovery from microorganisms / Chris M. Farnet and Emmanuel Zazopoulos -- Developments in strain improvement technology: evolutionary engineering of industrial microorganisms through gene, pathway, and genome shuffling / Stephen B. del Cardayr -- The discovery of anticancer drugs from natural sources / David J. Newman and Gordon M. Cragg -- Case studies in natural product optimization: novel antitumor agents derived from taxus brevifolia and catharanthus roseus / Jian Hong and Shu-Hui Chen --

Terpenoids as therapeutic drugs and pharmaceutical agents / Guangyi Wang, Weiping Tang and Robert R. Bidigare -- Challenges and opportunities in the Chinese herbal drug industry / Wei Jia and Lixin Zhang -- Arsenic trioxide and leukemia: from bedside to bench / Guo-Qiang Chen ... [et al.] -- New methods to access microbial diversity for small molecule discovery / Karsten Zengler, Ashish Paradkar, and Martin Keller -- Accessing the genomes of uncultivated microbes for novel natural products / Asuncion Martinez ... [et al.] -- New natural product diversity from marine actinomycetes / Paul R. Jensen and William Fenical -- Novel natural products from rainforest endophytes / Gary Strobel, Bryn Daisy, and Uvidelio Castillo -- Biological, economic, ecological, and legal aspects of harvesting traditional medicine in Ecuador / Alexandra Guevara-Aguirre and Ximena Chiriboga.