Chemogenomics in drug discovery :
Chemogenomics in drug discovery : a medicinal chemistry perspective /
edited by Hugo Kubinyi and Gerhard Müller.
- Weinheim : Wiley-VCH, c2004.
- xxiv, 463 p. : ill. (some col.) ; 25 cm.
- Methods and principles in medicinal chemistry ; v. 22 .
Includes bibliographical references and index.
Target family-directed masterkeyes in chemogenomics / Drug discovery from side effects / The value of chemical genetics in drug discovery / Structural aspects of binding site similarity: a 3D upgrade for chemogenomics / The contribution of molecular informatics to chemogenomics: knowledge-based discovery of biological targets and chemical lead compounds / Chemical kinomics / Structural aspects of kinases and their inhibitors / A chemical genomics approach for ion channel modulators / Phosphodiesterase inhibitors: a chemogenomic view / Proteochemometrics: a tool for modeling the molecular interaction space / Some principles related to chemogenomics in compound library and template design for GPCRs / Computational filters in lead generation: targeting drug-like chemotypes / Navigation in chemical space: ligand-based design of focused compound libraries / Natural product-derived compound libraries and protein structure similarity as guiding principles for the discovery of drug candidates / Combinatorial chemistry in the age of chemical genomics / Gehard Müller -- Hugo Kubinyi -- Keith Russell and William F. Michne -- Andreas Bergner and Judith Günther -- Edgar Jacoby, Ansgar Schuffenhauer, and Pierre Acklin -- Bert M. Klebl, Henrik Daub, and György Kéri -- Rogier Buijsman -- Karl-Heinz Baringhaus and Gerhard Hessler -- Martin Hendrix and Christopher Kallus -- Jarl E.S. Wikberg, Maris Lapinsch, and Peteris Prusis -- Thomas R. Webb -- Wolfgang Guba and Olivier Roche -- Gisbert Schneider and Petra Schneider -- Marcus A. Koch and Herbert Waldmann -- Reni Joseph and Prabhat Arya.
352730987X (hbk. : alk. paper)
2006436643
GBA444183
Pharmaceutical chemistry.
Drug development.
Chemogenomics.
Pharmacogenetics.
Drug Discovery--methods.
Combinatorial Chemistry Techniques.
Drug Design.
Genomics.
Médicaments--Développement.
Chimie pharmaceutique.
Médicaments--Recherche.
Médicaments--Conception.
RS403 / .C43 2004
615/.19
W1 / ME9613H v.22 2004 QV 38 / C517 2004
Includes bibliographical references and index.
Target family-directed masterkeyes in chemogenomics / Drug discovery from side effects / The value of chemical genetics in drug discovery / Structural aspects of binding site similarity: a 3D upgrade for chemogenomics / The contribution of molecular informatics to chemogenomics: knowledge-based discovery of biological targets and chemical lead compounds / Chemical kinomics / Structural aspects of kinases and their inhibitors / A chemical genomics approach for ion channel modulators / Phosphodiesterase inhibitors: a chemogenomic view / Proteochemometrics: a tool for modeling the molecular interaction space / Some principles related to chemogenomics in compound library and template design for GPCRs / Computational filters in lead generation: targeting drug-like chemotypes / Navigation in chemical space: ligand-based design of focused compound libraries / Natural product-derived compound libraries and protein structure similarity as guiding principles for the discovery of drug candidates / Combinatorial chemistry in the age of chemical genomics / Gehard Müller -- Hugo Kubinyi -- Keith Russell and William F. Michne -- Andreas Bergner and Judith Günther -- Edgar Jacoby, Ansgar Schuffenhauer, and Pierre Acklin -- Bert M. Klebl, Henrik Daub, and György Kéri -- Rogier Buijsman -- Karl-Heinz Baringhaus and Gerhard Hessler -- Martin Hendrix and Christopher Kallus -- Jarl E.S. Wikberg, Maris Lapinsch, and Peteris Prusis -- Thomas R. Webb -- Wolfgang Guba and Olivier Roche -- Gisbert Schneider and Petra Schneider -- Marcus A. Koch and Herbert Waldmann -- Reni Joseph and Prabhat Arya.
352730987X (hbk. : alk. paper)
2006436643
GBA444183
Pharmaceutical chemistry.
Drug development.
Chemogenomics.
Pharmacogenetics.
Drug Discovery--methods.
Combinatorial Chemistry Techniques.
Drug Design.
Genomics.
Médicaments--Développement.
Chimie pharmaceutique.
Médicaments--Recherche.
Médicaments--Conception.
RS403 / .C43 2004
615/.19
W1 / ME9613H v.22 2004 QV 38 / C517 2004