000			03596cam a22005174a 4500
001			14485196
003			I12T
005			20161209165031.0
008			060807s2004 gw a b 001 0 eng c
010			_a 2006436643
015			_aGBA444183
020			_a352730987X (hbk. : alk. paper)
035			_a(OCoLC)ocm56515194
040			_aNLM _cNLM _dERL _dUKM _dBUF _dOCLCQ _dOHX _dOCL _dBAKER _dMUQ _dDLC
042			_apcc
050	0	0	_aRS403 _b.C43 2004
060	0	0	_aW1 _bME9613H v.22 2004
060	1	0	_aQV 38 _bC517 2004
082	0	0	_a615/.19 _222
245	0	0	_aChemogenomics in drug discovery : _ba medicinal chemistry perspective / _cedited by Hugo Kubinyi and Gerhard Müller.
260			_aWeinheim : _bWiley-VCH, _cc2004.
300			_axxiv, 463 p. : _bill. (some col.) ; _c25 cm.
440		0	_aMethods and principles in medicinal chemistry ; _vv. 22
504			_aIncludes bibliographical references and index.
505	0	0	_tTarget family-directed masterkeyes in chemogenomics / _rGehard Müller -- _tDrug discovery from side effects / _rHugo Kubinyi -- _tThe value of chemical genetics in drug discovery / _rKeith Russell and William F. Michne -- _tStructural aspects of binding site similarity: a 3D upgrade for chemogenomics / _rAndreas Bergner and Judith Günther -- _tThe contribution of molecular informatics to chemogenomics: knowledge-based discovery of biological targets and chemical lead compounds / _rEdgar Jacoby, Ansgar Schuffenhauer, and Pierre Acklin -- _tChemical kinomics / _rBert M. Klebl, Henrik Daub, and György Kéri -- _tStructural aspects of kinases and their inhibitors / _rRogier Buijsman -- _tA chemical genomics approach for ion channel modulators / _rKarl-Heinz Baringhaus and Gerhard Hessler -- _tPhosphodiesterase inhibitors: a chemogenomic view / _rMartin Hendrix and Christopher Kallus -- _tProteochemometrics: a tool for modeling the molecular interaction space / _rJarl E.S. Wikberg, Maris Lapinsch, and Peteris Prusis -- _tSome principles related to chemogenomics in compound library and template design for GPCRs / _rThomas R. Webb -- _tComputational filters in lead generation: targeting drug-like chemotypes / _rWolfgang Guba and Olivier Roche -- _tNavigation in chemical space: ligand-based design of focused compound libraries / _rGisbert Schneider and Petra Schneider -- _tNatural product-derived compound libraries and protein structure similarity as guiding principles for the discovery of drug candidates / _rMarcus A. Koch and Herbert Waldmann -- _tCombinatorial chemistry in the age of chemical genomics / _rReni Joseph and Prabhat Arya.
650		0	_aPharmaceutical chemistry.
650		0	_aDrug development.
650		0	_aChemogenomics.
650	1	2	_aPharmacogenetics.
650	1	2	_aDrug Discovery _xmethods.
650	2	2	_aCombinatorial Chemistry Techniques.
650	2	2	_aDrug Design.
650	2	2	_aGenomics.
650		6	_aMédicaments _xDéveloppement.
650		6	_aChimie pharmaceutique.
650		6	_aMédicaments _xRecherche.
650		6	_aMédicaments _xConception.
700	1		_aKubinyi, Hugo.
700	1		_aMüller, Gerhard, _d1963-
856	4	2	_3Contributor biographical information _uhttp://www.loc.gov/catdir/enhancements/fy0643/2006436643-b.html
856	4	2	_3Publisher description _uhttp://www.loc.gov/catdir/enhancements/fy0643/2006436643-d.html
856	4	1	_3Table of contents only _uhttp://www.loc.gov/catdir/enhancements/fy0643/2006436643-t.html
906			_a7 _bcbc _cpccadap _d2 _encip _f20 _gy-gencatlg
942			_2udc _cBK
999			_c19177 _d19177