TY  - BOOK
AU  - Kubinyi,Hugo
AU  - Müller,Gerhard
TI  - Chemogenomics in drug discovery: a medicinal chemistry perspective 
SN  - 352730987X (hbk. : alk. paper)
AV  - RS403 .C43 2004
U1  - 615/.19 22
PY  - 2004///
CY  - Weinheim
PB  - Wiley-VCH
KW  - Pharmaceutical chemistry
KW  - Drug development
KW  - Chemogenomics
KW  - Pharmacogenetics
KW  - Drug Discovery
KW  - methods
KW  - Combinatorial Chemistry Techniques
KW  - Drug Design
KW  - Genomics
KW  - Médicaments
KW  - Développement
KW  - Chimie pharmaceutique
KW  - Recherche
KW  - Conception
N1  - Includes bibliographical references and index; Target family-directed masterkeyes in chemogenomics; Gehard Müller --; Drug discovery from side effects; Hugo Kubinyi --; The value of chemical genetics in drug discovery; Keith Russell and William F. Michne --; Structural aspects of binding site similarity: a 3D upgrade for chemogenomics; Andreas Bergner and Judith Günther --; The contribution of molecular informatics to chemogenomics: knowledge-based discovery of biological targets and chemical lead compounds; Edgar Jacoby, Ansgar Schuffenhauer, and Pierre Acklin --; Chemical kinomics; Bert M. Klebl, Henrik Daub, and György Kéri --; Structural aspects of kinases and their inhibitors; Rogier Buijsman --; A chemical genomics approach for ion channel modulators; Karl-Heinz Baringhaus and Gerhard Hessler --; Phosphodiesterase inhibitors: a chemogenomic view; Martin Hendrix and Christopher Kallus --; Proteochemometrics: a tool for modeling the molecular interaction space; Jarl E.S. Wikberg, Maris Lapinsch, and Peteris Prusis --; Some principles related to chemogenomics in compound library and template design for GPCRs; Thomas R. Webb --; Computational filters in lead generation: targeting drug-like chemotypes; Wolfgang Guba and Olivier Roche --; Navigation in chemical space: ligand-based design of focused compound libraries; Gisbert Schneider and Petra Schneider --; Natural product-derived compound libraries and protein structure similarity as guiding principles for the discovery of drug candidates; Marcus A. Koch and Herbert Waldmann --; Combinatorial chemistry in the age of chemical genomics; Reni Joseph and Prabhat Arya
UR  - http://www.loc.gov/catdir/enhancements/fy0643/2006436643-b.html
UR  - http://www.loc.gov/catdir/enhancements/fy0643/2006436643-d.html
UR  - http://www.loc.gov/catdir/enhancements/fy0643/2006436643-t.html
ER  -